Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7933036 | 0.89 | SLC22A12 (0.31) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4482811 | 0.88 | HTR1A (0.32) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7935667 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL4461269 | 0.79 | SLC6A2 (0.32) | — | |
| SCHEMBL4094237 | 0.78 | HTR7 (0.36) | HTR1AHTR7 | |
| SCHEMBL8204448 | 0.76 | DHFR (0.34) | HTR1AHTR7 | |
| SCHEMBL8202026 | 0.76 | HTR7 (0.34) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7938954 | 0.74 | — | — | |
| SCHEMBL7252936 | 0.74 | ALDH1A1 (0.36) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7935405 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |