Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945993 | 0.86 | KMT2A (0.49) | LMNACASP3POLBMAPTMAPK1 | |
| SCHEMBL7945044 | 0.85 | RAB9A (0.52) | LMNACASP3POLBMAPTMAPK1 | |
| SCHEMBL12205841 | 0.75 | G6PD (0.65) | GAAL3MBTL1CASP3ADRA2CMEN1 | |
| SCHEMBL15195144 | 0.69 | S1PR1 (0.44) | LMNACASP3SMN1; SMN2CASP7 | |
| SCHEMBL12230833 | 0.68 | CASP3 (0.53) | GAAL3MBTL1LMNACASP3POLB | |
| SCHEMBL19538842 | 0.66 | L3MBTL1 (0.76) | GAAL3MBTL1LMNAPOLBADRA2C | |
| SCHEMBL18415456 | 0.65 | GAA (0.63) | GAAL3MBTL1LMNAPOLBADRA2C | |
| SCHEMBL10027978 | 0.64 | ADRA2C (0.79) | GAAL3MBTL1LMNAPOLBADRA2C | |
| SCHEMBL18415528 | 0.64 | ADRA2C (0.68) | GAAL3MBTL1LMNAPOLBADRA2C | |
| SCHEMBL10784048 | 0.64 | ADRA2C (0.68) | GAAL3MBTL1LMNAPOLBADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513295-B2 | Viral and fungal inhibitors | GEORGETOWN UNIVERSITY (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513295-B2 | Viral and fungal inhibitors | GEORGETOWN UNIVERSITY (US) | 2013-08-20 | — | — | US | disclosed |
| US-20110301208-A1 | VIRAL AND FUNGAL INHIBITORS | WICHITA STATE UNIVERSITY (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301208-A1 | VIRAL AND FUNGAL INHIBITORS | WICHITA STATE UNIVERSITY (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2010039534-A2 | VIRAL AND FUNGAL INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301208-A1 | VIRAL AND FUNGAL INHIBITORS | HAVCR2, ZC3HAV1, ERG28 | GAA 79/4885L3MBTL1 2181/4885LMNA 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.