Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942668 | 0.86 | SLC6A2 (0.51) | ALDH1A1MAPTSMN1; SMN2TSHRDRD4 | |
| SCHEMBL7940933 | 0.83 | DRD2 (0.55) | MAPTDRD4DRD3DRD2 | |
| SCHEMBL7944691 | 0.75 | RAB9A (0.44) | ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL8053407 | 0.72 | MEN1 (0.47) | DRD2 | |
| Hydrochloric Acid SCHEMBL8143284 | 0.71 | MEN1 (0.46) | DRD2 | |
| SCHEMBL7933353 | 0.71 | DRD4 (0.50) | ALDH1A1MAPTSMN1; SMN2TSHRDRD4 | |
| SCHEMBL7939807 | 0.70 | HTR1A (0.56) | DRD4DRD3DRD2 | |
| SCHEMBL13698422 | 0.69 | KDM4E (0.55) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL7939817 | 0.69 | MAPK1 (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2DRD4 | |
| SCHEMBL13568797 | 0.69 | ALDH1A1 (0.71) | ALDH1A1CASP1CASP7KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | claimed |
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |