Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934714 | 0.87 | MAPT (0.36) | MAPK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7939410 | 0.84 | ALDH1A1 (0.38) | MAPK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7944340 | 0.82 | MAPT (0.36) | MEN1KMT2ACCR5MAPTALDH1A1 | |
| SCHEMBL7940148 | 0.81 | CD274 (0.35) | CCR5TSHRKDM4ESMN1; SMN2HPGD | |
| SCHEMBL3233357 | 0.77 | MEN1 (0.47) | MAPK1MEN1KMT2ACCR5 | |
| SCHEMBL3626707 | 0.76 | MEN1 (0.48) | MAPK1MEN1KMT2ACCR5MAPT | |
| SCHEMBL15153415 | 0.74 | GUCY1B2 (0.49) | — | |
| SCHEMBL7941720 | 0.71 | HTT (0.52) | MAPK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7940020 | 0.71 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL3995161 | 0.70 | CCR5 (0.51) | MAPK1MEN1KMT2ACCR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015652-A2 | THIAZOLE COMPOUNDS AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-11 | — | — | WO | disclosed |