Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944969 | 0.73 | LTA4H (0.30) | — | |
| SCHEMBL10435815 | 0.70 | SETD7 (0.37) | SETD7CYP1A2LMNACYP2D6ALOX15 | |
| SCHEMBL218178 | 0.70 | SETD7 (0.36) | SETD7CYP1A2LMNACYP2D6ALOX15 | |
| SCHEMBL705034 | 0.70 | LTA4H (0.47) | LMNACHRM2HTR1ACHRM1DRD2 | |
| SCHEMBL5077508 | 0.69 | LMNA (0.34) | SETD7CYP1A2LMNACYP2D6ALOX15 | |
| SCHEMBL756302 | 0.67 | LMNA (0.41) | SETD7CYP1A2LMNACYP2D6ALOX15 | |
| SCHEMBL28453301 | 0.66 | CA1 (0.48) | CYP1A2LMNACYP2D6TP53HTR1A | |
| SCHEMBL3295650 | 0.66 | CYP2C19 (0.38) | CYP1A2CYP2D6DRD2TSHRMEN1 | |
| SCHEMBL3295646 | 0.65 | ACHE (0.38) | LMNADRD2TSHRDRD3CYP3A4 | |
| SCHEMBL219213 | 0.65 | SETD7 (0.42) | SETD7CYP1A2LMNACYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137677-A2 | CATALYST AND PROCESS FOR OLEFIN POLYMERIZATION | BOREALIS A/S (DK) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034341-A2 | CATALYST AND PROCESS FOR OLEFIN POLYMERIZATION | BOREALIS A/S (DK) | 2000-06-15 | — | — | WO | disclosed |