Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM4B | O94953 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17313462 | 0.83 | TDP2 (0.47) | LOXL2SMN1; SMN2KDM4ETSHRCDC25B | |
| SCHEMBL8686875 | 0.81 | MTNR1A (0.56) | LOXL2SMN1; SMN2KDM4EGAATSHR | |
| SCHEMBL11665605 | 0.81 | LOXL2 (0.62) | LOXL2KDM4EGAACDC25BTHRB | |
| SCHEMBL3199606 | 0.76 | EGFR (0.51) | SMN1; SMN2KDM4ETSHREGFRPOLB | |
| SCHEMBL6046763 | 0.75 | LOXL2 (0.68) | LOXL2SMN1; SMN2KDM4EGAACDC25B | |
| SCHEMBL1720643 | 0.75 | LOXL2 (0.68) | LOXL2SMN1; SMN2KDM4EGAACDC25B | |
| SCHEMBL30853483 | 0.75 | KDM4E (0.53) | LOXL2KDM4EGAACDC25BTHRB | |
| SCHEMBL1872809 | 0.75 | KDM4E (0.53) | LOXL2KDM4EGAACDC25BTHRB | |
| SCHEMBL7260927 | 0.75 | LOXL2 (0.58) | LOXL2SMN1; SMN2KDM4EGAACDC25B | |
| SCHEMBL6645515 | 0.74 | TNKS (0.62) | LOXL2KDM4EGAACDC25BTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039534-A2 | VIRAL AND FUNGAL INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2010-04-08 | — | — | WO | disclosed |