SCHEMBL7946304

SCHEMBL7946304

CS(=O)(=O)c1ccc(Br)c(Cl)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PTGS2 P35354 10/20 0.37
ACLY P53396 2/20 0.34
HSD11B1 P28845 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7948238 0.78 LMNA (0.44) LMNAACLY
SCHEMBL3118107 0.76 CCR2 (0.38) L3MBTL1LMNA
SCHEMBL7946301 0.73 ACLY (0.44) L3MBTL1LMNAPTGS2ACLY
SCHEMBL31001623 0.73 CCR2 (0.38) L3MBTL1LMNAPTGS2
SCHEMBL8176124 0.73 CCR2 (0.38) L3MBTL1LMNAPTGS2
SCHEMBL9448525 0.73 CCR2 (0.40) L3MBTL1HSD11B1
SCHEMBL16564198 0.72 WDR5 (0.38) L3MBTL1NPSR1
SCHEMBL3823919 0.71 CA1 (0.40) L3MBTL1LMNAPTGS2
SCHEMBL9448405 0.71 LMNA (0.37) LMNA
SCHEMBL2781407 0.71 CA1 (0.43) L3MBTL1HSD11B1MCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265606-B1 TO CONTROL A BROAD SPECTRUM OF UNDESIRABLE VEGETATION, ARE SELECTIVE TO MAJOR CROPS, HAVE DESIRABLE ENVIRONMENTAL PROFILES, DOW AGROSCIENCES LLC 2001-07-24 US disclosed
US-6010981-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-01-04 US disclosed
EP-0914317-A2 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES Dow AgroSciences LLC (US) 1999-05-12 EP disclosed
WO-1998052926-A2 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 1998-11-26 WO disclosed