Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455825 | 0.86 | ASIC3 (0.49) | ALDH1A1GRM5ASIC3EGFRL3MBTL1 | |
| SCHEMBL5633251 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MELKGRM5ASIC3KDM4E | |
| SCHEMBL3456778 | 0.82 | HTR2C (0.46) | ALDH1A1GRM5ASIC3KDM4EEGFR | |
| SCHEMBL11548200 | 0.80 | MMP2 (0.37) | ALDH1A1MELKKDM4EMMP2MMP12 | |
| SCHEMBL29779956 | 0.80 | GRM5 (0.53) | ALDH1A1GRM5MAPK1C1SPARP1 | |
| SCHEMBL1375869 | 0.80 | GRM5 (0.53) | ALDH1A1GRM5MAPK1C1SPARP1 | |
| SCHEMBL24040098 | 0.80 | GRM5 (0.44) | ALDH1A1GRM5L3MBTL1MAPK1C1S | |
| SCHEMBL30422943 | 0.78 | HSD17B13 (0.47) | ALDH1A1MELKGRM5KDM4ELMNA | |
| SCHEMBL25201198 | 0.78 | HSD17B13 (0.47) | ALDH1A1MELKGRM5KDM4ELMNA | |
| SCHEMBL3456622 | 0.77 | GRM5 (0.39) | ALDH1A1GRM5ASIC3MAPK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717371-B | Preparation method of low-viscosity reactive flame-retardant polyether polyol, reactive flame-retardant heat-conducting polyurethane electronic pouring sealant and preparation method thereof | 山东一诺威新材料有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-113717371-A | Preparation method of low-viscosity reactive flame-retardant polyether polyol, reactive flame-retardant heat-conducting polyurethane electronic pouring sealant and preparation method thereof | 山东一诺威新材料有限公司 | 2021-11-30 | — | — | CN | claimed |
| US-12071436-B2 | Anti-parasitic compounds and uses thereof | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2024-08-27 | — | — | US | disclosed |
| CN-113717371-B | Preparation method of low-viscosity reactive flame-retardant polyether polyol, reactive flame-retardant heat-conducting polyurethane electronic pouring sealant and preparation method thereof | 山东一诺威新材料有限公司 | 2023-11-10 | — | — | CN | disclosed |
| US-20220340557-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2022-10-27 | — | — | US | disclosed |
| CN-113717371-A | Preparation method of low-viscosity reactive flame-retardant polyether polyol, reactive flame-retardant heat-conducting polyurethane electronic pouring sealant and preparation method thereof | 山东一诺威新材料有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-11180492-B2 | Anti-parasitic compounds and uses thereof | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20190002463-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2019-01-03 | — | — | US | disclosed |
| WO-2017124087-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-07-20 | — | — | WO | disclosed |
| WO-2017124087-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-07-20 | — | — | WO | disclosed |
| EP-2168944-B1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-11 | — | — | EP | disclosed |
| EP-2168944-B1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-11 | — | — | EP | disclosed |
| US-8129361-B2 | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129361-B2 | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-15 | — | — | US | disclosed |
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-15 | — | — | US | disclosed |
| EP-2168944-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-2168944-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180492-B2 | Anti-parasitic compounds and uses thereof | MPO, GOT2, GOT1 | ALDH1A1 1465/4885MELK 3002/4885GRM5 2612/4885 |
| US-12071436-B2 | Anti-parasitic compounds and uses thereof | MPO, GOT2, GOT1 | ALDH1A1 1465/4885MELK 3002/4885GRM5 2612/4885 |
| US-20220340557-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MPO, GOT2, GOT1 | ALDH1A1 1465/4885MELK 3002/4885GRM5 2612/4885 |
| US-20190002463-A1 | ANTI-PARASITIC COMPOUNDS AND USES THEREOF | MPO, GOT2, GOT1 | ALDH1A1 1465/4885MELK 3002/4885GRM5 2612/4885 |
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HLA-B, HLA-A, HLA-C | ALDH1A1 646/4885MELK 783/4885GRM5 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.