Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 8/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953261 | 0.84 | GRM2 (0.35) | SLC18A3KCNH2 | |
| SCHEMBL7953252 | 0.84 | CCR2 (0.35) | KCNH2 | |
| SCHEMBL7965929 | 0.74 | HTR1A (0.62) | HTR1ASLC6A4 | |
| SCHEMBL30987490 | 0.68 | CYP11B2 (0.47) | SLC18A3HTR1AHTR7 | |
| SCHEMBL13842724 | 0.66 | CYP11B2 (0.57) | LMNA | |
| SCHEMBL7887638 | 0.65 | HTR1A (0.65) | HTR1ASLC6A4 | |
| SCHEMBL7953116 | 0.64 | MAPT (0.47) | ADRB2ADRB1ADRB3HTR1AHTR7 | |
| SCHEMBL7881056 | 0.64 | HTR1A (0.64) | HTR1ASLC6A4 | |
| SCHEMBL11603165 | 0.64 | DRD4 (0.72) | ADRB1HTR1AKCNH2LMNASLC6A4 | |
| Hydrochloric Acid SCHEMBL11602209 | 0.63 | DRD4 (0.71) | KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |