Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | Q9HBH1 | 1/20 | 0.31 | |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448756 | 0.79 | MMP1 (0.37) | ITGB1ITGA4ITGB3ITGB7ITGAV | |
| SCHEMBL6969302 | 0.78 | ITGB3 (0.42) | ITGB1ITGA4ITGB3ITGAVCPB2 | |
| SCHEMBL12512388 | 0.76 | MMP1 (0.37) | ITGB3ITGAVCA12CA9CA2 | |
| SCHEMBL18762472 | 0.67 | ALDH1A1 (0.44) | ITGB3ITGAVCPB2MMP1MMP7 | |
| SCHEMBL18762585 | 0.67 | ALDH1A1 (0.44) | ITGB3ITGAVCPB2MMP1MMP7 | |
| Trifluoroacetic Acid SCHEMBL31111964 | 0.66 | APLNR (0.38) | CA2L3MBTL1 | |
| SCHEMBL29761845 | 0.66 | EPHX1 (0.37) | ITGB3ITGAVCA12CA9MMP1 | |
| Trifluoroacetic Acid SCHEMBL7953714 | 0.66 | CAD (0.33) | CA12CA9CA2SMN1; SMN2L3MBTL1 | |
| SCHEMBL23792556 | 0.65 | PADI1 (0.58) | ITGB3PADI1PADI4ITGA2BSMN1; SMN2 | |
| SCHEMBL11308981 | 0.65 | METAP2 (0.44) | MMP1MMP7MMP12ECE1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |