Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945633 | 0.89 | UCHL1 (0.34) | UCHL1USP30HDAC1HDAC6GLA | |
| SCHEMBL7954292 | 0.82 | ADH1A (0.32) | HDAC1HDAC6 | |
| SCHEMBL16568925 | 0.76 | ADH1A (0.40) | USP30HDAC1HDAC6CYP1A2POLB | |
| SCHEMBL16569047 | 0.76 | ADH1A (0.40) | USP30HDAC1HDAC6CYP1A2POLB | |
| SCHEMBL7952301 | 0.74 | UCHL1 (0.34) | UCHL1USP30HDAC1HDAC6CYP1A2 | |
| SCHEMBL6618596 | 0.69 | ADH1A (0.46) | CYP1A2GLAGAAFTOXDH | |
| SCHEMBL6852340 | 0.69 | ADH1A (0.44) | — | |
| SCHEMBL18406671 | 0.68 | CYP1A2 (0.35) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL6206095 | 0.67 | XDH (0.40) | UCHL1USP30HDAC1HDAC6XDH | |
| SCHEMBL6205393 | 0.67 | HDAC1 (0.35) | HDAC1HDAC6XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281354-B1 | ANTIBIOTICS; ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-28 | — | — | US | disclosed |