Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973958 | 0.89 | LMNA (0.38) | HRH4HRH3BRS3KDM4CKDM5B | |
| SCHEMBL7969216 | 0.89 | BRS3 (0.37) | FNTAPGGT1BHCAR2BRS3 | |
| SCHEMBL7958183 | 0.67 | CPA1 (0.46) | FNTAPGGT1BHCAR2HDAC1KDM4C | |
| SCHEMBL7971080 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL7970889 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL7958185 | 0.65 | CYP11B1 (0.39) | FNTAPGGT1BHNF4AKDM4CKDM5B | |
| SCHEMBL10503730 | 0.61 | MAPK1 (0.42) | KDM4CCYP2C9 | |
| SCHEMBL9786926 | 0.60 | HNF4A (0.92) | HNF4AACMSD | |
| SCHEMBL14100191 | 0.59 | ALDH1A1 (0.53) | HNF4ACYP2C9 | |
| SCHEMBL27896433 | 0.59 | ABCC1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |