Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.53 |
| ▸ | DRD2 | P14416 | 7/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957650 | 0.88 | ADRA1A (0.56) | DRD2MCHR1DRD3DRD4 | |
| SCHEMBL7963985 | 0.88 | DRD2 (0.52) | CCR2DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7961236 | 0.88 | CCR2 (0.46) | CCR2DRD2PRCP | |
| SCHEMBL7964064 | 0.88 | CCR2 (0.48) | CCR2DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7949578 | 0.87 | DRD2 (0.46) | CCR2DRD2MCHR1DRD3HTR1A | |
| SCHEMBL7949640 | 0.85 | DRD2 (0.54) | CCR2DRD2 | |
| SCHEMBL7961256 | 0.85 | CCR2 (0.39) | CCR2DRD2MCHR1 | |
| SCHEMBL7963813 | 0.85 | ADRA1A (0.47) | CCR2DRD2 | |
| SCHEMBL7957632 | 0.83 | CCR2 (0.42) | CCR2DRD2DRD3DRD4 | |
| SCHEMBL7961177 | 0.83 | OPRL1 (0.44) | CCR2DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |