Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961222 | 0.76 | OPRM1 (0.36) | TSHROPRM1OPRL1 | |
| SCHEMBL7971401 | 0.67 | LMNA (0.40) | MMP2MMP3MMP9TSHRKIF11 | |
| SCHEMBL7972666 | 0.66 | CYP4F2 (0.45) | — | |
| SCHEMBL7974599 | 0.63 | CYP4F2 (0.44) | — | |
| SCHEMBL7974393 | 0.61 | CYP4F2 (0.46) | — | |
| SCHEMBL31147300 | 0.58 | ADORA1 (0.36) | TSHRCYP19A1 | |
| SCHEMBL14788892 | 0.57 | MMP9 (0.72) | MMP2MMP3MMP9 | |
| SCHEMBL8923932 | 0.57 | GRIN2D (0.48) | MMP2MMP3MMP9CYP19A1 | |
| SCHEMBL8311348 | 0.56 | OPRM1 (0.33) | TSHROPRM1OPRL1 | |
| SCHEMBL3938866 | 0.56 | OPRM1 (0.37) | MMP2MMP3MMP9TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |