Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.49 |
| ▸ | HTR3B | O95264 | 3/20 | 0.49 |
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9601527 | 0.81 | DRD3 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL7549992 | 0.81 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7547987 | 0.74 | SIGMAR1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7962146 | 0.74 | HTR3E (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8957667 | 0.72 | SIGMAR1 (0.57) | SLC6A3SLC6A4SLC6A2SIGMAR1CYP2D6 | |
| SCHEMBL7951461 | 0.70 | LMNA (0.46) | HTR1ASLC6A3SLC6A4SLC6A2DRD2 | |
| SCHEMBL30819029 | 0.70 | HTR3E (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9725026 | 0.68 | HTR1A (0.70) | HTR1ADRD2DRD3HTR2AHRH1 | |
| SCHEMBL9209449 | 0.68 | MPO (0.62) | HTR1ASLC6A4HTR7 | |
| SCHEMBL2383995 | 0.68 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326371-B1 | ANTISEROTININE AGENTS | PHARMACIA AKTIEBOLAG (SE) | 2001-12-04 | — | — | US | disclosed |
| US-5652240-A | PSYCHOLOGICAL DISORDERS; ANXIOLYTIC AGENTS, ANTIDEPRESSANTS | PHARMACIA AKTIEBOLAG (SE) | 1997-07-29 | — | — | US | disclosed |