Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961725 | 0.86 | DRD3 (0.32) | SLC6A4 | |
| SCHEMBL7953974 | 0.78 | HTR1A (0.41) | ABCB1NPC1HPGDRAB9ASMN1; SMN2 | |
| Phenylacetic Acid SCHEMBL7961720 | 0.75 | P2RX7 (0.30) | — | |
| SCHEMBL7965741 | 0.69 | HTR1A (0.54) | ADRB1HTR1ASLC6A4 | |
| SCHEMBL7963760 | 0.66 | KDM4E (0.45) | ABCB1MAPTKDM4EMAPK1HTR1A | |
| SCHEMBL7967123 | 0.66 | ABCB1 (0.58) | ABCB1 | |
| SCHEMBL7963266 | 0.64 | SMN1; SMN2 (0.39) | ABCB1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7965451 | 0.64 | SMN1; SMN2 (0.55) | NPC1HPGDRAB9ASMN1; SMN2MAPT | |
| Succinic Acid SCHEMBL7965777 | 0.64 | ABCB1 (0.48) | ABCB1MAPTHTR1A | |
| SCHEMBL7965342 | 0.64 | KMT2A (0.44) | ABCB1NPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |