Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18937212 | 0.71 | L3MBTL1 (0.35) | BRD4ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL19235507 | 0.70 | BRD4 (0.36) | BRD4ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL14491564 | 0.70 | BRD4 (0.36) | BRD4ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL8435245 | 0.69 | MGLL (0.43) | ALDH1A1LMNA | |
| SCHEMBL23029099 | 0.68 | BRD4 (0.35) | BRD4ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL18937487 | 0.68 | BRD4 (0.35) | BRD4ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL8768481 | 0.67 | CYP1A2 (0.33) | BRD4ALDH1A1LMNAPOLB | |
| SCHEMBL26940381 | 0.67 | KDM4E (0.42) | ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL6217047 | 0.65 | ADORA2B (0.38) | BRD4ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL8589752 | 0.65 | BRD4 (0.34) | BRD4ALDH1A1LMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271357-B1 | REACTING SYNTHON WITH HYDRAZINE MOIETY WITH A SYNTHON HAVING ALDEHYDE MOIETY TO FORM COMPOUNDS THAT MIMIC OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. | 2001-08-07 | — | — | US | disclosed |
| US-6121433-A | FOR DIAGNOSTIC, RESEARCH AND THERAPEUTIC USE; MIMIC OR MODULATE PROTEINS, ENZYMES, NUCLEIC ACIDS AND LIPIDS | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0746326-A4 | OLIGOMERIC COMPOUNDS HAVING NITROGEN-CONTAINING LINKAGES | ISIS PHARMACEUTICALS INC (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5783682-A | Oligonucleotide mimics having nitrogen-containing linkages | ISIS PHARMACEUTICALS, INC. (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0746326-A1 | OLIGOMERIC COMPOUNDS HAVING NITROGEN-CONTAINING LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995018623-A1 | OLIGOMERIC COMPOUNDS HAVING NITROGEN-CONTAINING LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |