Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417880 | 0.78 | — | — | |
| SCHEMBL8696410 | 0.71 | ATAD2 (0.38) | CYP1A2POLBCYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL11869254 | 0.70 | BRPF1 (0.35) | CYP1A2POLBCYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL3806347 | 0.70 | FEN1 (0.38) | CYP1A2POLBCYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL9972888 | 0.68 | ALDH1A1 (0.40) | CYP1A2POLBCYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL24665501 | 0.67 | ALDH1A1 (0.39) | CYP1A2POLBCYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL7964135 | 0.67 | BRD4 (0.35) | POLBALDH1A1BRD4LMNA | |
| SCHEMBL15125556 | 0.67 | DRD2 (0.43) | CYP1A2POLBCYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL22511462 | 0.66 | ADORA2B (0.49) | CYP1A2CYP2D6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL25980045 | 0.64 | LMNA (0.46) | POLBALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |