Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.41 |
| ▸ | MMP2 | P08253 | 14/20 | 0.41 |
| ▸ | MMP9 | P14780 | 14/20 | 0.41 |
| ▸ | MMP8 | P22894 | 14/20 | 0.41 |
| ▸ | MMP13 | P45452 | 14/20 | 0.41 |
| ▸ | CA2 | P00918 | 11/20 | 0.41 |
| ▸ | CA1 | P00915 | 9/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7966881 | 0.98 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL7968724 | 0.98 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL7972093 | 0.98 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL2891322 | 0.98 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL25246586 | 0.95 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6880862 | 0.95 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL4154859 | 0.87 | MMP1 (0.39) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL770760 | 0.84 | MMP1 (0.46) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8773070 | 0.84 | MMP1 (0.39) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7971831 | 0.83 | MMP1 (0.45) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306204-B1 | REDUCTION OF INTERCOLOR BLEED, UNIFORM INK IMAGE; USED IN A MULTI-COLOR INK JET PRINTING PROCESS TO OBTAIN MULTI-COLOR INK JET IMAGES AT A HIGH SPEED | XEROX CORPORATION | 2001-10-23 | — | — | US | disclosed |
| EP-0784663-A4 | AQUEOUS METAL COATING COMPOSITION AND PROCESS WITH IMPROVED WETTING OF OILY OR SIMILARLY SOILED SURFACES | HENKEL CORP (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0784663-A1 | AQUEOUS METAL COATING COMPOSITION AND PROCESS WITH IMPROVED WETTING OF OILY OR SIMILARLY SOILED SURFACES | HENKEL CORPORATION (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011247-A1 | AQUEOUS METAL COATING COMPOSITION AND PROCESS WITH IMPROVED WETTING OF OILY OR SIMILARLY SOILED SURFACES | HENKEL CORPORATION (US) | 1996-04-18 | — | — | WO | disclosed |