Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 10/20 | 0.39 |
| ▸ | CA1 known ✓ | P00915 | 8/20 | 0.39 |
| ▸ | ABCC8 known ✓ | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 known ✓ | Q14654 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 11/20 | 0.39 |
| ▸ | MMP2 | P08253 | 11/20 | 0.39 |
| ▸ | MMP9 | P14780 | 11/20 | 0.39 |
| ▸ | MMP8 | P22894 | 11/20 | 0.39 |
| ▸ | MMP13 | P45452 | 11/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL4154859 | 0.97 | MMP1 (0.39) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL25246586 | 0.88 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6880862 | 0.85 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL7968724 | 0.85 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7956159 | 0.85 | MMP1 (0.43) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL7972093 | 0.85 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL5436074 | 0.85 | MMP1 (0.43) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL7966881 | 0.85 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL2891322 | 0.85 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| Potassium Ion SCHEMBL7966004 | 0.84 | MMP1 (0.41) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476521-B1 | Silver halide photographic material and method for processing the same | FUJI PHOTO FILM CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0475191-B1 | Method for producing silver halide photographic emulsion | FUJI PHOTO FILM CO LTD (JP) | 1997-10-29 | — | — | EP | disclosed |
| US-5674675-A | SILVER HALIDE EMULSION LAYER INCLUDES COLLOIDAL SILICA; IMPROVED PRESSURE RESISTANCE WITHOUT LOWERING PHOTOGRAPHIC SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1997-10-07 | — | — | US | disclosed |
| US-5498511-A | BLACK AND WHITE, ASCORBIC ACID DEVELOPER, A TELLURIUM AND/OR A SELENIUM SENSITIZER, SILVER THIOCYANATE, SILVER SELENOCYANATE | FUJI PHOTO FILM CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5348849-A | Reduction sensitization, antifogging agents | FUJI PHOTO FILM CO., LTD. (JP) | 1994-09-20 | — | — | US | disclosed |
| US-5310636-A | Silver iodide, less roller marks when developed in automatic processor | FUJI PHOTO FILM CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5298192-A | Scratch resistance | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5290655-A | Light sensitive silver halide emulsions with sensitizers on a support | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5283161-A | Developing mateiral containing compounds which reduce pressure sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0280252-B1 | Silver halide photographic material and method for forming super high contrast image therewith | FUJI PHOTO FILM CO LTD (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5230993-A | Subbing layer having cationic polymer, ammonium or phosphonium salts; for medical use or nondestructive testing | FUJI PHOTO FILM CO., LTD. (JP) | 1993-07-27 | — | — | US | disclosed |
| US-5206134-A | Adding simultaneously silver nitrate and metal iodide solutions or adding fine particles of silver iodide and/or silver iodobromide, producing grains with low surface iodide content | FUJI PHOTO FILM CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5190855-A | Hydroxypolyazaindene Complexing Agent | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0476521-A2 | Silver halide photographic material and method for processing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0475191-A2 | Method for producing silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-5028520-A | Polyhydroxybenzene Compound, Reduction of Reflection Index, Crossover Elimination | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| US-5015562-A | Light-sensitive silver halide element containing modant, dye and sonic polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-14 | — | — | US | disclosed |
| US-4965170-A | REDUCIBLE, TIME-RELEASING DYE COMPOUND; NONDIFFUSING; ANTISOILANTS; ALSO INCLUDING A HIGH-CONTRAST HYDRAZINE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| US-4942114-A | FLUORESCENT, REFLECTIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-17 | — | — | US | disclosed |
| EP-0280252-A2 | Silver halide photographic material and method for forming super high contrast image therewith | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-31 | — | — | EP | disclosed |