Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966503 | 0.85 | MEN1 (0.46) | KDM4EALDH1A1MEN1KMT2AIGF1R | |
| Oxalic Acid SCHEMBL7966526 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL7962754 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL7965014 | 0.84 | OPRM1 (0.43) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL7966082 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL7964658 | 0.73 | MEN1 (0.48) | ALDH1A1MEN1LMNAKMT2AEGFR | |
| Oxalic Acid SCHEMBL7966500 | 0.72 | KMT2A (0.52) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| Oxalic Acid SCHEMBL7965012 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2DRD3DRD2 | |
| SCHEMBL7966189 | 0.71 | LTA4H (0.50) | ALDH1A1MEN1LMNAKMT2AEGFR | |
| Hydrochloric Acid SCHEMBL29427652 | 0.70 | DRD3 (0.68) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |