Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963819 | 0.86 | MAOA (0.46) | OPRM1OPRD1MAPTMAOAMAOB | |
| Oxalic Acid SCHEMBL7965012 | 0.86 | KDM4E (0.46) | OPRM1OPRD1MAOAMAOBALDH1A1 | |
| SCHEMBL7966533 | 0.84 | KDM4E (0.47) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7966503 | 0.81 | MEN1 (0.46) | ALDH1A1KMT2ATSHRMEN1KDM4E | |
| SCHEMBL7964394 | 0.73 | OPRL1 (0.43) | OPRM1OPRD1HTR7SLC6A4 | |
| SCHEMBL7964392 | 0.72 | CYP1A2 (0.58) | MAPTNPSR1KMT2AUSP2MEN1 | |
| SCHEMBL7964386 | 0.71 | LMNA (0.39) | OPRM1OPRD1HPGDMAPTNPSR1 | |
| Oxalic Acid SCHEMBL7966526 | 0.70 | KDM4E (0.54) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7964899 | 0.70 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1KMT2ATSHR | |
| SCHEMBL7962754 | 0.69 | ALDH1A1 (0.56) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |