Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966346 | 0.86 | CYP2D6 (0.49) | MEN1KMT2ACYP2D6TSHRALDH1A1 | |
| Oxalic Acid SCHEMBL7966500 | 0.86 | KMT2A (0.52) | MEN1KMT2ACYP2D6TSHRALDH1A1 | |
| SCHEMBL7966533 | 0.85 | KDM4E (0.47) | MEN1KMT2AALDH1A1KDM4EHTR2A | |
| SCHEMBL7965014 | 0.81 | OPRM1 (0.43) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL7966526 | 0.71 | KDM4E (0.54) | MEN1KMT2AALDH1A1KDM4EHTR7 | |
| SCHEMBL7965519 | 0.70 | ALDH1A1 (0.51) | MEN1KMT2ACYP2D6ALDH1A1CYP1A2 | |
| SCHEMBL7962754 | 0.70 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1KDM4EHTR7 | |
| SCHEMBL7964899 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2ACYP2D6TSHRALDH1A1 | |
| SCHEMBL7970239 | 0.68 | GAA (0.43) | MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7953964 | 0.68 | HTR1A (0.40) | MEN1KMT2AALDH1A1HTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |