Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.51 |
| ▸ | FABP3 | P05413 | 3/20 | 0.51 |
| ▸ | DHODH | Q02127 | 7/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978016 | 0.87 | PLA2G2A (0.47) | KDM4EPOLBMAPTNPC1RAB9A | |
| SCHEMBL7984061 | 0.84 | CACNB4 (0.42) | FABP4FABP3KDM4EMAPTNPSR1 | |
| SCHEMBL8802957 | 0.83 | ESRRB (0.38) | ESRRBESRRAKDM4EPOLBMAPT | |
| SCHEMBL8801316 | 0.78 | IMPDH2 (0.40) | ESRRBESRRAKDM4EMAPTNPC1 | |
| SCHEMBL7983845 | 0.69 | LMNA (0.50) | KDM4EPOLBMAPTMEN1KMT2A | |
| SCHEMBL7979243 | 0.69 | CACNB4 (0.38) | MAPTNPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL21083000 | 0.68 | FABP4 (1.00) | FABP4FABP3DHODHKDM4EMAPT | |
| SCHEMBL8803269 | 0.67 | LMNA (0.39) | FABP4FABP3KDM4EPOLBMAPT | |
| SCHEMBL8801276 | 0.66 | KMT2A (0.41) | KDM4EPOLBMAPTMEN1KMT2A | |
| SCHEMBL4506174 | 0.66 | TP53 (0.55) | FABP4FABP3KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | disclosed |