Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPEPLD | Q6IQ20 | 8/20 | 0.35 |
| ▸ | TPH1 | P17752 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701795 | 0.72 | LTB4R (0.43) | NAPEPLD | |
| SCHEMBL8702051 | 0.72 | NOTUM (0.40) | NAPEPLDTPH1ALDH1A1STAT6 | |
| SCHEMBL6503428 | 0.72 | NOTUM (0.40) | NAPEPLDTPH1ALDH1A1STAT6 | |
| SCHEMBL27868110 | 0.71 | OPRM1 (0.51) | KDM4E | |
| SCHEMBL6249500 | 0.71 | OPRK1 (0.49) | NAPEPLD | |
| SCHEMBL16333323 | 0.71 | OPRK1 (0.40) | NAPEPLDGAA | |
| SCHEMBL6250215 | 0.70 | OPRK1 (0.50) | NAPEPLD | |
| SCHEMBL6984380 | 0.69 | NAPEPLD (0.40) | NAPEPLDKDM4EALDH1A1MAPTGAA | |
| SCHEMBL6251298 | 0.69 | CYP2D6 (0.52) | NAPEPLD | |
| SCHEMBL9389648 | 0.67 | RORC (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010011091-A1 | Analgesics | ITO FUMITAKA (JP) | 2001-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011091-A1 | Analgesics | OPRL1, OPRK1, OPRD1 | NAPEPLD 200/4885TPH1 38/4885PIK3CD 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.