Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971973 | 0.82 | GPR84 (0.39) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7968952 | 0.78 | KDM4E (0.38) | MAOBCHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7968407 | 0.74 | POLB (0.46) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7972384 | 0.73 | KDM4E (0.35) | MAOBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6026174 | 0.69 | ESR2 (0.40) | MAOBMAPTALDH1A1TDP1MEN1 | |
| SCHEMBL6026268 | 0.69 | CFTR (0.39) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7956293 | 0.69 | TLR8 (0.39) | MAOBCHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7972386 | 0.68 | MAPT (0.40) | MAPTALDH1A1THRBMEN1KMT2A | |
| SCHEMBL7966269 | 0.68 | LMNA (0.40) | MAOBMAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7972422 | 0.67 | GPR84 (0.39) | MAOBMAPTALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |