Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979149 | 0.94 | NPC1 (0.39) | ALDH1A1MEN1KMT2ANPSR1NPC1 | |
| SCHEMBL7993224 | 0.88 | MEN1 (0.42) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL7980536 | 0.84 | PTGDR2 (0.35) | NPC1RAB9AHDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL7982833 | 0.81 | PKM (0.33) | KMT2ANPC1RAB9A | |
| SCHEMBL7946743 | 0.81 | MITF (0.45) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL7951886 | 0.81 | MITF (0.45) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL7947062 | 0.81 | MITF (0.43) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL7979470 | 0.81 | MAPK1 (0.36) | ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL7982224 | 0.80 | RAB9A (0.34) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL7969219 | 0.79 | KMT2A (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |