Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951892 | 0.90 | POLB (0.39) | MAPK1ALDH1A1NPSR1APLNRNPC1 | |
| SCHEMBL7979149 | 0.84 | NPC1 (0.39) | ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL7980536 | 0.83 | PTGDR2 (0.35) | NPC1RAB9A | |
| SCHEMBL7982833 | 0.82 | PKM (0.33) | NPC1RAB9A | |
| SCHEMBL7969219 | 0.82 | KMT2A (0.34) | — | |
| SCHEMBL7945520 | 0.82 | NPC1 (0.39) | ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL7969240 | 0.81 | ALDH1A1 (0.36) | ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL7944071 | 0.80 | HTT (0.40) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7982206 | 0.79 | POLB (0.36) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7969063 | 0.79 | CYP2D6 (0.42) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |