Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980536 | 0.88 | PTGDR2 (0.35) | RAB9APKMHSD11B1OPRM1OPRD1 | |
| SCHEMBL7947285 | 0.86 | HPGD (0.36) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7948263 | 0.86 | HPGD (0.36) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7982833 | 0.85 | PKM (0.33) | RAB9APKMKMT2AOPRM1OPRD1 | |
| SCHEMBL7969073 | 0.85 | MTNR1B (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7979149 | 0.83 | NPC1 (0.39) | RAB9AMEN1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL7969219 | 0.83 | KMT2A (0.34) | PKMCHRM3ALOX15MEN1KMT2A | |
| SCHEMBL7938405 | 0.80 | FKBP1A (0.38) | CHRM3MEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7969240 | 0.80 | ALDH1A1 (0.36) | RAB9AMEN1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL7979470 | 0.79 | MAPK1 (0.36) | RAB9AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |