Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966346 | 0.81 | CYP2D6 (0.49) | LMNAMEN1KMT2AKDM4EPOLB | |
| SCHEMBL7965519 | 0.80 | ALDH1A1 (0.51) | GAALMNAMEN1KMT2AKDM4E | |
| SCHEMBL7964899 | 0.78 | ALDH1A1 (0.50) | LMNAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL7962754 | 0.78 | ALDH1A1 (0.56) | LMNAMEN1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7816305 | 0.78 | SMN1; SMN2 (0.53) | KMT2AKDM4ESMN1; SMN2 | |
| Oxalic Acid SCHEMBL7966500 | 0.77 | KMT2A (0.52) | LMNAMEN1KMT2AKDM4EPOLB | |
| SCHEMBL7967101 | 0.77 | HTR1A (0.40) | — | |
| SCHEMBL7963819 | 0.77 | MAOA (0.46) | NPC1RAB9ALMNAMAPT | |
| SCHEMBL7964658 | 0.75 | MEN1 (0.48) | NPC1RAB9ALMNAMEN1KMT2A | |
| Oxalic Acid SCHEMBL7966526 | 0.75 | KDM4E (0.54) | NPC1RAB9ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006082-A2 | TREATMENT OF ANXIETY DISORDERS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |