Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.40 |
| ▸ | NAAA | Q02083 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977162 | 0.82 | NAAA (0.40) | ACHENAAA | |
| SCHEMBL7972951 | 0.82 | LMNA (0.39) | NAAAEPHX1 | |
| SCHEMBL7972860 | 0.76 | KDM4E (0.46) | MEN1KMT2A | |
| SCHEMBL7961496 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL10812054 | 0.73 | ACHE (0.67) | ACHEMEN1KMT2AEPHX1 | |
| SCHEMBL16673943 | 0.72 | ACHE (0.63) | ACHEMEN1KMT2AEPHX1 | |
| SCHEMBL7974359 | 0.71 | TSHR (0.44) | — | |
| SCHEMBL7972638 | 0.70 | MAPT (0.55) | NAAAMEN1KMT2A | |
| SCHEMBL7974425 | 0.70 | — | — | |
| SCHEMBL25277844 | 0.69 | ACHE (0.71) | ACHENAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |