Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 13/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974363 | 0.83 | NAAA (0.37) | NAAAASAH1 | |
| SCHEMBL7971215 | 0.82 | ACHE (0.40) | NAAAACHE | |
| SCHEMBL7974714 | 0.80 | MAPT (0.35) | — | |
| SCHEMBL7974358 | 0.77 | KDM4E (0.43) | — | |
| SCHEMBL7971395 | 0.76 | ALDH1A1 (0.44) | — | |
| SCHEMBL7977404 | 0.76 | MAPT (0.46) | — | |
| SCHEMBL10812054 | 0.72 | ACHE (0.67) | ACHE | |
| SCHEMBL16673943 | 0.70 | ACHE (0.63) | ACHE | |
| SCHEMBL25220749 | 0.67 | ACHE (0.71) | NAAAACHE | |
| SCHEMBL25228774 | 0.67 | ACHE (0.71) | NAAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |