Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961134 | 0.81 | HCAR2 (0.31) | — | |
| SCHEMBL7974358 | 0.81 | KDM4E (0.43) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL7972951 | 0.78 | LMNA (0.39) | — | |
| SCHEMBL7971215 | 0.76 | ACHE (0.40) | MEN1KMT2A | |
| SCHEMBL23471393 | 0.74 | KDM4E (0.64) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL23471410 | 0.72 | KDM4E (0.60) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL7961373 | 0.72 | CA2 (0.33) | — | |
| SCHEMBL8291459 | 0.72 | DRD3 (0.58) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL24115530 | 0.70 | SIGMAR1 (0.59) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL7974359 | 0.70 | TSHR (0.44) | KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |