Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499284 | 0.88 | ALAD (0.35) | KMOCA12POLB | |
| SCHEMBL7931561 | 0.85 | SLC6A3 (0.45) | SLC6A2SLC6A3 | |
| SCHEMBL7929550 | 0.85 | RXRA (0.37) | — | |
| SCHEMBL7974920 | 0.84 | BCL2L1 (0.39) | CA12CA9KMT2A | |
| SCHEMBL7929501 | 0.83 | MCL1 (0.39) | CA12CA9S1PR1 | |
| SCHEMBL7970423 | 0.81 | HAO1 (0.35) | — | |
| SCHEMBL7972143 | 0.81 | PGR (0.36) | MEN1POLBKMT2A | |
| SCHEMBL7931034 | 0.80 | MAPT (0.41) | CA12CA9MEN1KMT2A | |
| SCHEMBL7931169 | 0.80 | CA12 (0.39) | CA12CA9 | |
| SCHEMBL7972312 | 0.80 | CCR5 (0.38) | CA12CA9S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |