Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991532 | 0.88 | SMN1; SMN2 (0.43) | CYP11B1CYP11B2ALDH1A1HIF1AHPGD | |
| SCHEMBL7985492 | 0.88 | SMN1; SMN2 (0.42) | ALDH1A1HIF1AF2F12HPGD | |
| SCHEMBL7992177 | 0.87 | SMN1; SMN2 (0.42) | CYP11B1CYP11B2HIF1AGRM5LMNA | |
| SCHEMBL7974007 | 0.87 | KDM4C (0.41) | CYP11B1CYP11B2ALDH1A1GRM5LMNA | |
| SCHEMBL7985456 | 0.87 | GAA (0.48) | ALDH1A1HIF1AGRM5SMN1; SMN2MAPT | |
| SCHEMBL7974268 | 0.86 | CYP11B1 (0.48) | CYP11B1CYP11B2ALDH1A1HPGDNPSR1 | |
| SCHEMBL7974309 | 0.84 | CYP11B1 (0.45) | CYP11B1CYP11B2ALDH1A1HPGDLMNA | |
| SCHEMBL7988747 | 0.84 | CYP11B1 (0.44) | CYP11B1CYP11B2ALDH1A1HPGDLMNA | |
| SCHEMBL7985236 | 0.82 | LMNA (0.44) | CYP11B1CYP11B2ALDH1A1HPGDLMNA | |
| SCHEMBL7974247 | 0.82 | CYP11B1 (0.44) | CYP11B1CYP11B2ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |