Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | LPO | P22079 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974018 | 0.87 | GAA (0.53) | GAATP53RXFP1MEN1KMT2A | |
| SCHEMBL7991788 | 0.87 | CYP11B1 (0.46) | GAAHIF1APKMGRM5SMN1; SMN2 | |
| SCHEMBL7985850 | 0.85 | GAA (0.49) | GAATP53RXFP1ABCG2YTHDC1 | |
| SCHEMBL7985870 | 0.85 | GAA (0.50) | GAATP53RXFP1KMT2AYTHDC1 | |
| SCHEMBL7985492 | 0.85 | SMN1; SMN2 (0.42) | TP53MEN1KMT2AHIF1ANPC1 | |
| SCHEMBL7989313 | 0.85 | ROCK2 (0.52) | GAATP53RXFP1YTHDC1ROCK2 | |
| SCHEMBL7974007 | 0.85 | KDM4C (0.41) | FFAR1MEN1KMT2ANPC1GRM5 | |
| SCHEMBL7992177 | 0.85 | SMN1; SMN2 (0.42) | TP53FFAR1HIF1ANPC1PKM | |
| SCHEMBL7984696 | 0.83 | GAA (0.47) | GAATP53RXFP1ABCG2YTHDC1 | |
| SCHEMBL7974584 | 0.82 | GAA (0.56) | GAATP53RXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |