Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991635 | 0.94 | IDO1 (0.37) | HDAC1HDAC6HSD17B13BRD4CYP11B1 | |
| SCHEMBL7985791 | 0.94 | CYP11B1 (0.40) | HSD17B13BRD4CYP11B1CYP11B2EPHX2 | |
| SCHEMBL7987253 | 0.94 | HPGDS (0.40) | HDAC1HDAC6CYP11B1CYP11B2ACP1 | |
| SCHEMBL7985299 | 0.93 | CDK9 (0.39) | HDAC6HSD17B13BRD4CYP11B1CYP11B2 | |
| SCHEMBL7987310 | 0.92 | YTHDC1 (0.41) | HDAC1HDAC6HSD17B13CDK9ACP1 | |
| SCHEMBL7988958 | 0.92 | ALDH1A1 (0.42) | BRD4CYP11B1CYP11B2 | |
| SCHEMBL7985360 | 0.92 | POLB (0.40) | HDAC1HDAC6HSD17B13CDK9ACP1 | |
| SCHEMBL7988638 | 0.92 | MET (0.42) | HSD17B13BRD4CYP11B1CYP11B2EPHX2 | |
| SCHEMBL7988734 | 0.92 | MET (0.44) | HDAC1HDAC6HSD17B13CYP11B1CYP11B2 | |
| SCHEMBL7985264 | 0.90 | CYP11B1 (0.41) | HSD17B13BRD4CYP11B1CYP11B2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |