Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984937 | 0.94 | ADORA3 (0.52) | NPC1RAB9AADORA3KCNK3KCNK9 | |
| SCHEMBL7984455 | 0.90 | ABCB1 (0.54) | NPC1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7974029 | 0.89 | ADORA3 (0.50) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL7988231 | 0.89 | NPC1 (0.47) | NPC1RAB9AADORA3KCNK9KMT2A | |
| SCHEMBL7974265 | 0.88 | MCHR1 (0.47) | NPC1RAB9AADORA3MEN1KMT2A | |
| SCHEMBL7988637 | 0.87 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7975241 | 0.86 | GAA (0.50) | NTRK1NPC1RAB9AADORA3SMN1; SMN2 | |
| SCHEMBL7992368 | 0.86 | TP53 (0.47) | RAB9AMEN1KMT2AMAPTADRA1D | |
| SCHEMBL7984965 | 0.85 | ALDH1A1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7974040 | 0.85 | KDM4E (0.51) | NTRK1P2RY14NPC1RAB9AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |