Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991669 | 0.94 | HDAC1 (0.38) | HDAC1HDAC6CYP11B1CYP11B2ACP1 | |
| SCHEMBL7988734 | 0.93 | MET (0.44) | HDAC1HDAC6ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL7985791 | 0.93 | CYP11B1 (0.40) | HPGDSSMN1; SMN2ALDH1A1GAACYP11B1 | |
| SCHEMBL7987310 | 0.91 | YTHDC1 (0.41) | SMN1; SMN2HDAC1HDAC6MAPK1ACP1 | |
| SCHEMBL7974469 | 0.90 | HDAC1 (0.40) | HPGDSSMN1; SMN2HDAC1HDAC6CYP11B1 | |
| SCHEMBL7985360 | 0.89 | POLB (0.40) | SMN1; SMN2HDAC1HDAC6ACP1 | |
| SCHEMBL7988958 | 0.89 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7991635 | 0.89 | IDO1 (0.37) | HDAC1HDAC6CYP11B1CYP11B2ADORA2A | |
| SCHEMBL7984683 | 0.89 | CNOT7 (0.37) | ALDH1A1ADORA2AADORA1ADORA3 | |
| SCHEMBL7985336 | 0.88 | PIK3CA (0.42) | SMN1; SMN2HDAC1HDAC6ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |