Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216568 | 0.84 | CA2 (0.33) | CTSLPTGDR2ALDH1A1CA1CA2 | |
| SCHEMBL7931558 | 0.83 | CTSL (0.39) | CTSLPTGDR2KDM4EVEGFAMAPT | |
| SCHEMBL7974920 | 0.79 | BCL2L1 (0.39) | PTGDR2KDM4EKMT2ALMNA | |
| SCHEMBL6756663 | 0.78 | MAPK1 (0.35) | PTGDR2MEN1KMT2A | |
| SCHEMBL3499284 | 0.78 | ALAD (0.35) | PTGDR2SRD5A1SRD5A2VEGFA | |
| SCHEMBL7929501 | 0.78 | MCL1 (0.39) | PTGDR2MAPT | |
| Hydrochloric Acid SCHEMBL7922067 | 0.77 | MAPK1 (0.34) | PTGDR2MEN1KMT2ALMNA | |
| SCHEMBL7972704 | 0.77 | KMO (0.40) | MEN1KMT2A | |
| SCHEMBL7970423 | 0.76 | HAO1 (0.35) | — | |
| SCHEMBL7931169 | 0.75 | CA12 (0.39) | PTGDR2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |