Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973159 | 0.96 | MAPT (0.39) | MAPTTDP1ATML3MBTL1PTGES | |
| SCHEMBL7976100 | 0.92 | CYP24A1 (0.37) | TDP1PTGESSMN1; SMN2 | |
| SCHEMBL7065836 | 0.91 | MAPT (0.41) | MAPTTDP1ATML3MBTL1PTGES | |
| SCHEMBL7976225 | 0.88 | TDP1 (0.39) | TDP1PTGESSMN1; SMN2 | |
| SCHEMBL7972944 | 0.86 | KMT2A (0.39) | ATMSMN1; SMN2 | |
| SCHEMBL7969622 | 0.85 | TDP1 (0.42) | MAPTTDP1ATML3MBTL1SMN1; SMN2 | |
| SCHEMBL7976230 | 0.84 | CTRC (0.38) | TDP1L3MBTL1CTRCSMN1; SMN2 | |
| SCHEMBL7959970 | 0.84 | RAB9A (0.36) | — | |
| SCHEMBL7971433 | 0.83 | FKBP1A (0.38) | TDP1L3MBTL1PTGESSMN1; SMN2 | |
| SCHEMBL7971318 | 0.83 | CTRC (0.40) | TDP1L3MBTL1CTRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |