Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 7/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859709 | 0.87 | MAOB (0.49) | MAOBMAOAPRKCI | |
| SCHEMBL9027437 | 0.76 | MAOB (0.49) | MAOBHRH3MAOANR1I2LMNA | |
| SCHEMBL7976822 | 0.72 | ALDH1A1 (0.39) | MAOBMAOAPRKCI | |
| SCHEMBL5203864 | 0.70 | MAOB (0.69) | MAOBMAOAPRKCI | |
| SCHEMBL30821349 | 0.69 | MAPT (0.49) | MAOBHRH3 | |
| SCHEMBL7389121 | 0.69 | MAPT (0.49) | MAOBHRH3 | |
| SCHEMBL7716113 | 0.69 | PTPRC (0.46) | MAOBMAOAPRKCI | |
| SCHEMBL7974509 | 0.68 | CASP1 (0.44) | MAOBHRH3MAOAPRKCI | |
| SCHEMBL8319226 | 0.67 | BAZ2B (0.56) | MAOBMAOAPRKCI | |
| SCHEMBL5204433 | 0.67 | SRD5A2 (0.55) | MAOBMAOAPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277845-B1 | BONE DISEASE PROPHYLACTICS, ANTIMETASTASIS AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-08-21 | — | — | US | disclosed |