Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869876 | 0.77 | ACHE (0.42) | ALDH1A1ACHEBAZ2BMAOBMAOA | |
| SCHEMBL5203864 | 0.72 | MAOB (0.69) | MAOBMAOAPRKCICASP1CASP7 | |
| SCHEMBL7976706 | 0.72 | MAOB (0.39) | MAOBMAOAPRKCI | |
| SCHEMBL5204433 | 0.72 | SRD5A2 (0.55) | ALDH1A1BAZ2BMAOBMAOAPRKCI | |
| SCHEMBL7716113 | 0.70 | PTPRC (0.46) | ALDH1A1BAZ2BMAOBMAOAPRKCI | |
| SCHEMBL7974509 | 0.69 | CASP1 (0.44) | BAZ2BMAOBMAOAPRKCICASP1 | |
| SCHEMBL20244667 | 0.67 | ALDH1A1 (0.53) | ALDH1A1ACHEHSD17B10 | |
| SCHEMBL9854943 | 0.67 | CYP24A1 (0.43) | ACHE | |
| SCHEMBL5956228 | 0.67 | CASP1 (0.53) | MAOBMAOAPRKCICASP1CASP7 | |
| SCHEMBL4455438 | 0.66 | ALDH1A1 (0.54) | ALDH1A1ACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277845-B1 | BONE DISEASE PROPHYLACTICS, ANTIMETASTASIS AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-08-21 | — | — | US | disclosed |