Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870715 | 0.85 | CASP1 (0.59) | CASP1CASP7HSD17B10MAOBMAOA | |
| SCHEMBL5858951 | 0.82 | MAOA (0.61) | CASP1CASP7HSD17B10MAOBMAOA | |
| SCHEMBL5203864 | 0.79 | MAOB (0.69) | CASP1CASP7HSD17B10MAOBMAOA | |
| SCHEMBL5204433 | 0.76 | SRD5A2 (0.55) | CASP1CASP7HSD17B10MAOBMAOA | |
| SCHEMBL7716113 | 0.71 | PTPRC (0.46) | HSD17B10MAOBMAOAPRKCIBAZ2B | |
| SCHEMBL8871212 | 0.70 | PBRM1 (0.59) | CASP1CASP7HSD17B10MAOBMAOA | |
| SCHEMBL7976822 | 0.69 | ALDH1A1 (0.39) | CASP1CASP7HSD17B10MAOBMAOA | |
| SCHEMBL11849586 | 0.69 | MAOB (0.68) | MAOBMAOAPRKCIGRM5CYP2A6 | |
| SCHEMBL7112522 | 0.69 | MAOA (0.35) | CASP1CASP7HSD17B10MAOBMAOA | |
| SCHEMBL7637788 | 0.69 | PBRM1 (0.68) | CASP1CASP7HSD17B10MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277845-B1 | BONE DISEASE PROPHYLACTICS, ANTIMETASTASIS AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-08-21 | — | — | US | disclosed |