Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7967439 | 0.79 | ALDH1A1 (0.41) | RAB9AALDH1A1L3MBTL1TSHRLMNA | |
| SCHEMBL7966600 | 0.77 | NOS3 (0.47) | NPC1ADORA3RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL3324587 | 0.74 | LMNA (0.58) | NPC1GBA1RAB9AKMT2AMEN1 | |
| SCHEMBL7994913 | 0.73 | L3MBTL1 (0.43) | NPC1ADORA3RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL7966791 | 0.72 | RAB9A (0.61) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7994849 | 0.72 | EPHX2 (0.50) | NPC1GBA1ADORA3RAB9AALDH1A1 | |
| SCHEMBL2928853 | 0.72 | CNR2 (0.43) | ADORA3ALDH1A1L3MBTL1TSHRLMNA | |
| SCHEMBL7976984 | 0.71 | RAB9A (0.43) | NPC1RAB9AALDH1A1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL7984877 | 0.71 | EPHX2 (0.49) | NPC1GBA1ADORA3RAB9AALDH1A1 | |
| SCHEMBL2638097 | 0.71 | NPC1 (0.56) | NPC1GBA1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | disclosed |