Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964027 | 0.82 | POLB (0.71) | HPGDRXFP1ALDH1A1MAPTNPC1 | |
| SCHEMBL7974434 | 0.82 | POLB (0.65) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7964168 | 0.81 | POLB (0.70) | HPGDRXFP1ALDH1A1MAPTNPC1 | |
| SCHEMBL7977571 | 0.80 | NPC1 (0.53) | KMT2ANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7974413 | 0.80 | SMN1; SMN2 (0.59) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7974455 | 0.79 | TSHR (0.61) | NPSR1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL7977544 | 0.79 | LMNA (0.57) | KMT2ARXFP1KDM4EMAPTNPC1 | |
| SCHEMBL7977631 | 0.79 | CYP1A2 (0.52) | HPGDNPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL7980318 | 0.78 | HPGD (0.51) | HPGDNPSR1ALDH1A1MAPTNPC1 | |
| SCHEMBL7980366 | 0.78 | NPSR1 (0.63) | HPGDNPSR1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |