Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GRK2 | P25098 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977571 | 0.87 | NPC1 (0.53) | MAPK1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL7980318 | 0.84 | HPGD (0.51) | NPSR1MAPK1POLBMAPTTSHR | |
| SCHEMBL7977564 | 0.84 | POLB (0.50) | NPSR1MAPK1POLBLMNAALDH1A1 | |
| SCHEMBL7974413 | 0.83 | SMN1; SMN2 (0.59) | POLBLMNAGAAALDH1A1HPGD | |
| SCHEMBL7977544 | 0.81 | LMNA (0.57) | MAPTTSHRLMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL7974436 | 0.81 | ALDH1A1 (0.61) | NPSR1MAPK1MAPTGAAHSD17B10 | |
| SCHEMBL7980306 | 0.81 | NPSR1 (0.49) | NPSR1POLBTSHRGAATDP1 | |
| SCHEMBL7977587 | 0.80 | NPC1 (0.58) | POLBMAPTLMNAALDH1A1HPGD | |
| SCHEMBL7974288 | 0.80 | KMT2A (0.65) | POLBMAPTLMNAALDH1A1HPGD | |
| SCHEMBL7980389 | 0.80 | NPC1 (0.49) | NPSR1POLBMAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |