Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 8/20 | 0.38 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.36 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984012 | 0.84 | TRPV1 (0.37) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL7997967 | 0.80 | KDM4E (0.41) | MAPK10RAB9ACSNK1D | |
| SCHEMBL7996112 | 0.79 | RAB9A (0.51) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL7997945 | 0.79 | SMN1; SMN2 (0.36) | MAPK10CCNE1CDK2CDK5RAB9A | |
| SCHEMBL7998415 | 0.77 | KDM4E (0.39) | MAPK10RAB9ACSNK1D | |
| SCHEMBL7997959 | 0.76 | KDR (0.43) | RAB9A | |
| SCHEMBL7998311 | 0.75 | GLS (0.44) | MAPK8RAB9A | |
| SCHEMBL7978072 | 0.74 | ALDH1A1 (0.37) | RAB9ACSNK1D | |
| SCHEMBL5735113 | 0.74 | GAA (0.43) | — | |
| SCHEMBL7232438 | 0.74 | GLS (0.43) | MAPK8NLRP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055140-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |