Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974260 | 0.85 | CYP11B1 (0.47) | GAAHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7984754 | 0.84 | SMN1; SMN2 (0.47) | GAASMN1; SMN2L3MBTL1GLAHTT | |
| SCHEMBL7984208 | 0.84 | MAPT (0.39) | GAAHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7975252 | 0.83 | HPGD (0.45) | GAAHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7984512 | 0.82 | GAA (0.50) | GAAKMT2A | |
| SCHEMBL7985651 | 0.81 | CYP1A2 (0.41) | METGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7984378 | 0.78 | CYP11B1 (0.42) | METGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7988129 | 0.78 | MET (0.44) | METGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7987434 | 0.77 | CYP11B1 (0.42) | METHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7988660 | 0.77 | CYP11B1 (0.49) | GAAHPGDALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |