Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPY2R | P49146 | 3/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971528 | 0.86 | KMT2A (0.66) | TSHRLMNANPY2RHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6137360 | 0.85 | S1PR1 (0.51) | TSHRLMNANPY2RS1PR1HTT | |
| SCHEMBL7985451 | 0.84 | ALDH1A1 (0.54) | LMNANPY2RHTTALDH1A1KMT2A | |
| SCHEMBL7985106 | 0.82 | NPY2R (0.56) | LMNANPY2RALDH1A1KMT2AKDM4E | |
| SCHEMBL7985215 | 0.81 | L3MBTL1 (0.51) | NPY2RHTTALDH1A1NPC1KMT2A | |
| SCHEMBL7985330 | 0.80 | NPY2R (0.57) | LMNANPY2RHTTALDH1A1KMT2A | |
| SCHEMBL7982477 | 0.80 | SLC9A1 (0.69) | NPY2RALDH1A1NPC1KMT2ACYP2C19 | |
| SCHEMBL7982517 | 0.80 | RBP4 (0.54) | LMNANPY2RHTTALDH1A1KMT2A | |
| SCHEMBL7971257 | 0.80 | ALDH1A1 (0.59) | TSHRLMNAHTTALDH1A1NPC1 | |
| SCHEMBL7982405 | 0.80 | KMT2A (0.53) | NPY2RHTTALDH1A1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |